Dr. Trott's point of view
“NAD+ is the one infusion where patients consistently describe something real: clarity and stamina, like a full night's sleep you didn't have. Dosed slowly, it's a pleasure.”
Suzanne A. Trott, M.D., F.A.C.S.
About Dr. Trott →01
How I Administer It, And Why Slowly
The single most common mistake I see with NAD+ elsewhere is running it too fast. Infused quickly, it causes chest tightness, flushing, and nausea, and patients understandably never come back. I run roughly 250–500 mL over two to four hours, starting at the low end for first-timers, and I stay involved in the titration. For patients who cannot give up an afternoon, I use subcutaneous injections, a 30-gauge half-inch needle, about 10–12 mm into the abdominal fat pad, usually twice weekly between infusions.
02
Who I Think Should Actually Do This
I recommend NAD+ most often to patients preparing for or recovering from surgery, patients whose jobs live on airplanes, and patients focused seriously on longevity and metabolic health. A loading series of four to six weekly infusions, then monthly maintenance, is where I see real change; a single infusion is a nice afternoon, not a result. I review every medication and supplement first, blood pressure and psychiatric medications matter here, and I will tell you plainly if I do not think you need it.
References
Further reading & sources
- NAD+ metabolism in aging and cellular repairPubMed / National Library of Medicine
- Nicotinamide adenine dinucleotide precursors: clinical trialsPubMed / National Library of Medicine
- NAD biology overviewNCBI Bookshelf
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